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The half-life of nicotine is around 2 hours, while the half-life of cotinine is 7 to 40 hours

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The major expenditures, according to state contracts, were $1 million to Vilas Pharmacy of Pierre for tobacco cessation medications and $824,000 to Avera Health Plans to provide "telephone and other tobacco cessation counseling and support services for the SD Quitline." State records also indicate that the Department of Health signed a $175,000, one-year contract in June for South Dakota State University to conduct a study of the effectiveness of the South Dakota Quitline